Arrestin-biased allosteric modulator of neurotensin receptor 1 alleviates acute and chronic pain
Ran Guo, Chen Ouyang, Yang Zhou, Sangsu Bang, Sharat Chandra, Yize Li, Gang Chen, Rou‐Gang Xie, Wei He, Jing Xu, Richard Zhou, Shaoyong Song, Kelsey L. Person, Madelyn Moore, Abigail Alwin, Ivan Spasojević, Michael R. Jackson, Steven H. Olson, Marc G. Caron, Lauren M. Slosky, William C. Wetsel, Lawrence S Barak, Ru‐Rong Ji
Topics & Concepts
Allosteric modulatorAllosteric regulationNociceptionExcitatory postsynaptic potentialPharmacologyOpioidNeuroscienceNeuropathic painChronic painBiologyConditioned place preferenceMAPK/ERK pathwayReceptorSignal transductionMorphineInhibitory postsynaptic potentialMedicineInternal medicineCell biologyNeuropeptides and Animal PhysiologyReceptor Mechanisms and SignalingPain Mechanisms and Treatments