Identification of glutamine metabolism-related gene signature to predict colorectal cancer prognosis
Yang Xie, Jun Li, Qing Tao, Yonghui Wu, Zide Liu, Chunyan Zeng, Youxiang Chen
Abstract
In summary, we have successfully identified and comprehensively analyzed a gene signature associated with glutamine metabolism in CRC for the first time. This gene signature consistently and reliably predicts the prognosis of CRC patients, indicating its potential as a metabolic target for individuals with CRC.
Topics & Concepts
Colorectal cancerSignature (topology)Identification (biology)GlutamineGene signatureGeneComputational biologyCancerBiologyBioinformaticsMedicineOncologyGeneticsGene expressionMathematicsAmino acidBotanyGeometryCancer, Hypoxia, and MetabolismCancer Research and TreatmentsAmino Acid Enzymes and Metabolism