Oral Microbiome Dynamics and Surfactant Protein A Expression in Patients with Spontaneous Intraoral Lesions
Alejandro F. Ruiz, Hana Desta, Nur S. Ismail
Abstract
Oral ulcers develop when the epithelial lining of the oral mucosa is compromised, often leading to pain, redness, discomfort, and bleeding. While some ulcers are triggered by local trauma, systemic illnesses, or medications, the causes of many remain unclear. This pilot study explores the composition of saliva and the oral microbiome in individuals with atraumatic pre-ulcerous and ulcerous lesions, compared to healthy controls, while accounting for three prevalent risk factors: smoking, stress,
Topics & Concepts
Oral MicrobiomeSalivaMedicineMicrobiomeOral mucosaOral cavityImmunologyPulmonary surfactantPathologyMucosal lesionsDentistryMouth mucosaRisk factorOral microbiologyOral toleranceInflammationGastroenterologyAntibodyBioinformaticsInternal medicineSurfactant protein ADysbiosisImmune systemSalivary Gland Disorders and FunctionsOral microbiology and periodontitis researchOral Health Pathology and Treatment