The E3 ubiquitin ligase Peli1 regulates the metabolic actions of mTORC1 to suppress antitumor T cell responses
Chun‐Jung Ko, Lingyun Zhang, Zuliang Jie, Lele Zhu, Xiaofei Zhou, Xiaoping Xie, Tianxiao Gao, Jin‐Young Yang, Xuhong Cheng, Shao‐Cong Sun
Topics & Concepts
Ubiquitin ligaseBiologyUbiquitin-Protein LigasesUbiquitinDNA ligasemTORC1Cell biologyDNA LigasesCancer researchSignal transductionGeneticsGenePI3K/AKT/mTOR pathwayImmune Cell Function and InteractionCAR-T cell therapy researchUbiquitin and proteasome pathways