Centrifugal microfluidic system for colorimetric sample-to-answer detection of viral pathogens
Matthias Geißler, D. Brassard, Nadine Adam, Neda Nasheri, Ana Victoria C. Pilar, Kyle Tapp, Liviu Clime, Caroline Miville-Godin, Maxence Mounier, Christina Nassif, Ljuboje Lukic, Lidija Malic, Nathalie Corneau, Teodor Veres
Abstract
, seven) micropillar arrays in a narrow fluidic pathway can lead to variation (up to 50% or more) in the distribution of colorimetric signal deriving from the assay. Numerical modeling of flow behaviour was used to substantiate these findings. The technology-by virtue of automation-can provide a pathway toward rapid detection of viral pathogens, shortening response time in food safety surveillance, compliance, and enforcement as well as outbreak investigations.
Topics & Concepts
MicrofluidicsMicrofluidic chipLab-on-a-chipChipSample (material)MultiplexingWorkflowChromatographyNanotechnologyComputer scienceMaterials scienceChemistryDatabaseTelecommunicationsBiosensors and Analytical DetectionSARS-CoV-2 detection and testingViral gastroenteritis research and epidemiology