Anti-tumor efficacy of a potent and selective non-covalent KRASG12D inhibitor
Jill Hallin, Vickie Bowcut, Andrew Calinisan, David M. Briere, Lauren Hargis, Lars D. Engstrom, Jade Laguer, James Medwid, Darin Vanderpool, Ella T. Lifset, David Huy Trinh, Natalie Hoffman, Xiaolun Wang, J. David Lawson, Robin J. Gunn, Christopher R. Smith, Nicole C. Thomas, Matthew Martinson, Alex Bergstrom, Francis Sullivan, Karyn Bouhana, Shannon L. Winski, Leo He, Julio Fernandez-Banet, Adam Pavlı́ček, Jacob R. Haling, Lisa Rahbæk, Matthew A. Marx, Peter Olson, James G. Christensen
Topics & Concepts
KRASMutantCancer researchCell cultureBiologyChemistryMutationBiochemistryGeneGeneticsProtein Kinase Regulation and GTPase SignalingEnzyme Structure and FunctionMelanoma and MAPK Pathways