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Extracellular HMGB1 augments macrophage inflammation by facilitating the endosomal accumulation of ALD-DNA via TLR2/4-mediated endocytosis

Jincheng Lu, Yan Yue, Sidong Xiong

2021Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease31 citationsDOI

Topics & Concepts

HMGB1EndosomeEndocytosisInflammationMacrophageCell biologyNeutrophil extracellular trapsPathogenesisExtracellularChemistryBiologyImmunologyReceptorIntracellularBiochemistryIn vitroImmune Response and InflammationNeutrophil, Myeloperoxidase and Oxidative MechanismsT-cell and B-cell Immunology
Extracellular HMGB1 augments macrophage inflammation by facilitating the endosomal accumulation of ALD-DNA via TLR2/4-mediated endocytosis | Litcius