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Synthesis and structure–activity relationships of ticlopidine derivatives and analogs as inhibitors of ectonucleotidase CD39

Chunyang Bi, Laura Schäkel, Salahuddin Mirza, Katharina Sylvester, Julie Pelletier, Sang-Yong Lee, Thanigaimalai Pillaiyar, Jean Sévigny, Christa E. Müller

2023Bioorganic Chemistry11 citationsDOI

Topics & Concepts

ChemistryPurinergic receptorTiclopidineAllosteric regulationAdenosineNucleosideATP hydrolysisStereochemistryBiochemistryEnzymeClopidogrelAspirinATPaseAdenosine and Purinergic SignalingAdolescent and Pediatric HealthcareGenetics and Neurodevelopmental Disorders
Synthesis and structure–activity relationships of ticlopidine derivatives and analogs as inhibitors of ectonucleotidase CD39 | Litcius