A pH-responsive Pickering Nanoemulsion for specified spatial delivery of Immune Checkpoint Inhibitor and Chemotherapy agent to Tumors
Le Jia, Minghui Pang, Man Fan, Xuan Tan, Yiqian Wang, Meng-Lin Huang, Yijing Liu, Qin Wang, Yanhong Zhu, Xiangliang Yang
Abstract
This novel strategy highlights the promising potential of a universal platform to co-deliver different therapeutic or diagnostic reagents with spatial regulation to improve the anti-tumor effect.
Topics & Concepts
Tumor microenvironmentChemotherapyDrug deliveryDoxorubicinImmune systemIn vivoImmune checkpointCancer researchChemistryPharmacologyImmunotherapyMedicineImmunologyBiologySurgeryOrganic chemistryBiotechnologyNanoplatforms for cancer theranosticsNanoparticle-Based Drug DeliveryPhagocytosis and Immune Regulation