Tetrahydroindazole inhibitors of CDK2/cyclin complexes
Jae Chul Lee, Kwon Ho Hong, Andreas Becker, Joseph S. Tash, E. Schönbrunn, Gunda I. Georg
Topics & Concepts
Cyclin-dependent kinase 2ChemistryCyclin ACyclinCyclin ECyclin-dependent kinaseStereochemistryCyclin A2Binding siteEnzymeBiochemistryCell cycleCellProtein kinase ACancer-related Molecular PathwaysEpigenetics and DNA MethylationAdvanced Breast Cancer Therapies