Synthesis of New Bioactive Indolyl-1,2,4-Triazole Hybrids As Dual Inhibitors for EGFR/PARP-1 Targeting Breast and Liver Cancer Cells
Mohamed F. Youssef, Mohamed S. Nafie, Eid E. Salama, Ahmed T. A. Boraei, Emad M. Gad
Abstract
may serve as a promising anticancer activity through dual PARP-1/EGFR target inhibition.
Topics & Concepts
ChemistryCytotoxicityCancer cellMTT assayApoptosisTriazoleCancer researchCancerBiochemistryIn vitroBiologyOrganic chemistryGeneticsSynthesis and biological activityClick Chemistry and ApplicationsCancer therapeutics and mechanisms