Cleavage of E-cadherin by porcine respiratory bacterial pathogens facilitates airway epithelial barrier disruption and bacterial paracellular transmigration
Qi Cao, Wenbin Wei, Huan Wang, Zesong Wang, Yujin Lv, Menghong Dai, Chen Tan, Huanchun Chen, Xiangru Wang
Abstract
. This common pathogenic mechanism shared by other porcine respiratory bacterial pathogens explains how these bacterial pathogens destroy the airway epithelial cell barriers and proliferate in respiratory mucosal surface or other systemic tissues.
Topics & Concepts
BiologyParacellular transportMicrobiologyActinobacillus pleuropneumoniaeBordetella bronchisepticaMoraxella catarrhalisEctodomainRespiratory epitheliumEpitheliumHaemophilus influenzaeBacteriaBiochemistryMembraneSerotypePermeability (electromagnetism)AntibioticsReceptorGeneticsMicrobial infections and disease researchBacterial Infections and VaccinesAquaculture disease management and microbiota