A deprotonation pathway to reactive [B]CH<sub>2</sub> boraalkenes
Karel Škoch, Chaohuang Chen, Constantin G. Daniliuc, Gerald Kehr, Gerhard Erker
Abstract
The BH compounds IMes(Ar F )BH(NTf 2 ) (Ar F : C 6 F 5 or FpXyl) were converted to the IMes(Ar F )BCH 2 boraalkenes in a three step reaction sequence of B-methylation with methyllithium, hydride abstraction and deprotonation.
Topics & Concepts
ChemistryDeprotonationMoietyAdductMedicinal chemistryCycloadditionMethyllithiumReagentHydrideLewis acids and basesStereochemistryOrganic chemistryIonCatalysisMetalOrganoboron and organosilicon chemistryAsymmetric Hydrogenation and CatalysisCarbon dioxide utilization in catalysis