Inferring cellular and molecular processes in single-cell data with non-negative matrix factorization using Python, R and GenePattern Notebook implementations of CoGAPS
Jeanette Johnson, Ashley Tsang, Jacob T. Mitchell, David Zhou, Julia Bowden, Emily F. Davis-Marcisak, Thomas D. Sherman, Ted Liefeld, Melanie Loth, Loyal A. Goff, Jacquelyn W. Zimmerman, Ben Kinny-Köster, Elizabeth M. Jaffee, Pablo Tamayo, Jill P. Mesirov, Michael Reich, Elana J. Fertig, Genevieve Stein-O’Brien
Topics & Concepts
Python (programming language)Non-negative matrix factorizationComputer scienceMatrix decompositionImplementationGraphical user interfaceData miningProgramming languagePhysicsEigenvalues and eigenvectorsQuantum mechanicsSingle-cell and spatial transcriptomicsGene expression and cancer classificationGene Regulatory Network Analysis