A Pd-catalyzed route to carborane-fused boron heterocycles
Mengjie Zhu, Puzhao Wang, WU Zheng-qiu, Yangfa Zhong, Laiman Su, Yuquan Xin, Alexander M. Spokoyny, Chao Zou, Xin Mu
Abstract
A Pd-catalyzed cross-coupling system has been developed to achieve vicinal diamination of 9,10-dibromo-carborane with NH-heterocycles and anilines. These products can be further converted to carborane-fused six- and seven-membered heterocycles.
Topics & Concepts
CarboraneVicinalBoronCatalysisChemistryCombinatorial chemistryOrganic chemistryMedicinal chemistryBoron Compounds in ChemistryRadiopharmaceutical Chemistry and ApplicationsPharmacological Effects and Toxicity Studies