Inhibition of ER stress by targeting the IRE1α–TXNDC5 pathway alleviates crystalline silica-induced pulmonary fibrosis
Xi Chen, Chao Li, Jiali Liu, Yangyang He, Yungeng Wei, Jie Chen
Topics & Concepts
Unfolded protein responsePulmonary fibrosisEndoplasmic reticulumMedicineSilicosisGene knockdownFibrosisCancer researchChemistryInternal medicineCell biologyPathologyBiologyApoptosisBiochemistryEndoplasmic Reticulum Stress and DiseaseOccupational and environmental lung diseasesInterstitial Lung Diseases and Idiopathic Pulmonary Fibrosis