Litcius/Paper detail

Methylation of the central transcriptional regulator KLF4 by PRMT5 is required for DNA end resection and recombination

Cintia Checa-Rodríguez, Cristina Cepeda-García, Javier Ramón, Ana López-Saavedra, Fernando R. Balestra, María S. Domínguez-Sánchez, Daniel Gómez-Cabello, Pablo Huertas

2020DNA repair32 citationsDOIOpen Access PDF

Topics & Concepts

BiologyKLF4Homologous recombinationDNA repairDNA damageDNA methylationDownregulation and upregulationReprogrammingMethylationCell biologyProtein arginine methyltransferase 5GeneticsMethyltransferaseMolecular biologyCellDNASOX2GeneGene expressionTranscription factorCancer-related gene regulationEpigenetics and DNA MethylationKruppel-like factors research