Incidence, risk factors, timing, and outcome of influenza versus COVID-19–associated putative invasive aspergillosis
Camille Sarrazyn, Sofie Dhaese, Birgit Demey, Stefaan J. Vandecasteele, Marijke Reynders, Jens Van Praet
Abstract
To the Editor-Invasive pulmonary aspergillosis (IPA) is a wellestablished superinfection of influenza, especially in critically ill patients admitted to the intensive care unit (ICU). More recently, several reports have emerged of coronavirus disease 2019 (COVID-19)-associated IPA. 2-4 However, whether the risk and morbidity of IPA is comparable between both viral illnesses remains unclear. We compared the incidence, risk factors, timing, and outcome of influenza and COVID-19-associated IPA for the 2019-2020 season in our institution, a 1,182-bed acute-and tertiary-care hospital in Belgium consisting of 3 separate campuses.
Topics & Concepts
Coronavirus disease 2019 (COVID-19)Incidence (geometry)AspergillosisMedicine2019-20 coronavirus outbreakSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)VirologyImmunologyInternal medicineDiseaseInfectious disease (medical specialty)OpticsPhysicsOutbreakAntifungal resistance and susceptibilityRespiratory and Cough-Related ResearchFungal Infections and Studies