NPC1L1 and ABCG5/8 induction explain synergistic fecal cholesterol excretion in ob/ob mice co-treated with PPAR-α and LXR agonists
Rai Ajit K. Srivastava, Angelo B. Cefalù, Nishtha S. Srivastava, Maurizio Averna
Topics & Concepts
Liver X receptorInternal medicineEndocrinologyCholesterolReverse cholesterol transportExcretionABCA1FenofibrateAgonistChemistryCholesterol 7 alpha-hydroxylaseBiologyMedicineReceptorLipoproteinBiochemistryTransporterNuclear receptorGeneTranscription factorCholesterol and Lipid MetabolismDrug Transport and Resistance MechanismsPeroxisome Proliferator-Activated Receptors