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Identification of covalent inhibitors that disrupt M. tuberculosis growth by targeting multiple serine hydrolases involved in lipid metabolism

Brett M. Babin, Laura J. Keller, Yishay Pinto, Veronica L. Li, Andrew S. Eneim, Summer E. Vance, Stephanie M. Terrell, Ami S. Bhatt, Jonathan Z. Long, Matthew Bogyo

2021Cell chemical biology28 citationsDOIOpen Access PDF

Topics & Concepts

SerineMycobacterium tuberculosisBiogenesisEnzymeTuberculosisCell envelopeBiochemistryBiologyChemistryMicrobiologyGeneMedicineEscherichia coliPathologyTuberculosis Research and EpidemiologyBiochemical and Molecular ResearchPneumocystis jirovecii pneumonia detection and treatment
Identification of covalent inhibitors that disrupt M. tuberculosis growth by targeting multiple serine hydrolases involved in lipid metabolism | Litcius