Intranasal delivery of mitochondrial protein humanin rescues cell death and promotes mitochondrial function in Parkinson's disease
Kyung Hwa Kim
Abstract
: These data support a novel role of mitochondrial protein humanin in mitochondrial function and neuronal survival against Parkinson's disease, in which humanin treatment is sufficient for stimulating mitochondrial gene expression.
Topics & Concepts
Mitochondrial biogenesisNeuroprotectionMitochondrionCell biologyBiologyProtein kinase Bmitochondrial fusionMitochondrial DNASignal transductionPharmacologyBiochemistryGeneGDF15 and Related BiomarkersNuclear Receptors and SignalingNutrition and Health in Aging