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Reticulate allopolyploidy and subsequent dysploidy drive evolution and diversification in the cotton family

Rengang Zhang, Hang Zhao, Justin L. Conover, Hong‐Yun Shang, Detuan Liu, Minjie Zhou, Xiongfang Liu, Kai‐Hua Jia, Shi‐Cheng Shao, Meng‐Meng Li, Chong-Yang Jin, Yihui Liu, Xiao-Yi Shen, Dawei Li, Martin A. Lysák, Jonathan F. Wendel, Xiaoyang Ge, Yongpeng Ma

2025Nature Communications12 citationsDOIOpen Access PDF

Abstract

Abstract Polyploidy and subsequent post-polyploid diploidization (PPD) are key drivers of plant genome evolution, yet their contributions to evolutionary success remain debated. Here, we analyze the Malvaceae family as an exemplary system for elucidating the evolutionary role of polyploidy and PPD in angiosperms, leveraging 11 high-quality chromosome-scale genomes from all nine subfamilies, including newly sequenced, near telomere-to-telomere assemblies from four of these subfamilies. Our findings reveal a complex reticulate paleoallopolyploidy history early in the diversification of the Malvadendrina clade, characterized by multiple rounds of species radiation punctuated by ancient allotetraploidization (Mal-β) and allodecaploidization (Mal-α) events around the Cretaceous–Paleogene (K–Pg) boundary. We further reconstruct the evolutionary dynamics of PPD and find a strong correlation between dysploidy rate and taxonomic richness of the paleopolyploid subfamilies ( R 2 ≥ 0.90, P < 1e-4), supporting the “polyploidy for survival and PPD for success” hypothesis. Overall, our study provides a comprehensive reconstruction of the evolutionary history of the Malvaceae and underscores the crucial role of polyploidy–dysploidy waves in shaping plant biodiversity.

Topics & Concepts

BiologyPolyploidReticulateEvolutionary biologyReticulate evolutionPlant evolutionCladeGenomePhylogeneticsConcerted evolutionPhylogenetic treeGenome evolutionGeneticsBotanyGeneChromosomal and Genetic VariationsPlant Virus Research StudiesGenomics and Phylogenetic Studies