Natural loss of function of ephrin-B3 shapes spinal flight circuitry in birds
Baruch Haimson, Oren Meir, Reut Sudakevitz-Merzbach, Gerard Elberg, Samantha R. Friedrich, Peter V. Lovell, Sónia Paixão, Rüdiger Klein, Claudio V. Mello, Avihu Klar
Abstract
at the roof plate. Our findings support a role for loss of ephrin-B3 function in shaping the avian brachial spinal cord circuitry and facilitating synchronous wing flapping.
Topics & Concepts
Function (biology)WingBiologyNeuroscienceFlappingEvolutionary biologyAerospace engineeringEngineeringAxon Guidance and Neuronal SignalingZebrafish Biomedical Research ApplicationsNeurobiology and Insect Physiology Research