CatSper Calcium Channels: 20 Years On
Jae Yeon Hwang, Jean‐Ju Chung
Abstract
The flagellar-specific Ca 2+ channel CatSper is the predominant Ca 2+ entry site in mammalian sperm. CatSper-mediated Ca 2+ signaling affects nearly every event that regulates sperm to acquire fertilizing capability. In this review, we summarize some of the main findings from 20 years of CatSper research and highlight recent progress and prospects.
Topics & Concepts
CalciumVoltage-dependent calcium channelChemistryBiologyInternal medicineMedicineIon channel regulation and functionNeuroscience and Neuropharmacology ResearchNeuroscience and Neural Engineering