1H-1,2,3-triazole grafted tacrine-chalcone conjugates as potential cholinesterase inhibitors with the evaluation of their behavioral tests and oxidative stress in mice brain cells
Anu Rani, Amandeep Singh, Jashanpreet Kaur, Gurjit Singh, Rajbir Bhatti, Njabulo Joyfull Gumede, Prishani Kisten, Parvesh Singh, Sumanjit, Vipan Kumar
Topics & Concepts
ChemistryTacrineButyrylcholinesterasePharmacologyChalconeOxidative stressAcetylcholinesteraseLipid peroxidationGlutathioneCholinesteraseNeurochemicalIn vivoEx vivoTBARSAchéBiochemistryStereochemistryNeuroscienceEnzymeIn vitroPsychologyBiologyBiotechnologyMedicineCholinesterase and Neurodegenerative DiseasesComputational Drug Discovery MethodsPesticide Exposure and Toxicity