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Inhibition of the CCR6-CCL20 axis prevents regulatory T cell recruitment and sensitizes head and neck squamous cell carcinoma to radiation therapy

Cleopatra Rutihinda, Ryma Haroun, Nour Elhouda Saidi, Juan Pablo Ordoñez, Sahar Naasri, Dominique Lévesque, François‐Michel Boisvert, Pierre‐Hugues Fortier, Mathieu Belzile, Laurent Fradet, Vincent Hubert-Tremblay, Guy Anne Turgeon, Chang Shu Wang, Patrick Delage, Étienne Rousseau, Benoît Paquette, Ayman Oweida

2022Cancer Immunology Immunotherapy49 citationsDOIOpen Access PDF

Topics & Concepts

CCL20RadioresistanceCancer researchHead and neck squamous-cell carcinomaImmune systemChemokineTumor microenvironmentMedicineFlow cytometryImmunotherapyImmunologyBiologyRadiation therapyHead and neck cancerInternal medicineChemokine receptorChemokine receptors and signalingCancer Immunotherapy and BiomarkersImmune Cell Function and Interaction
Inhibition of the CCR6-CCL20 axis prevents regulatory T cell recruitment and sensitizes head and neck squamous cell carcinoma to radiation therapy | Litcius