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Genetic Mutations Associated with Isoniazid Resistance in Mycobacterium tuberculosis in Mongolia

Erdenegerel Narmandakh, Oyuntuya Tumenbayar, Tsetsegtuya Borolzoi, Baasansuren Erkhembayar, Tsolmon Boldoo, Naranzul Dambaa, Buyankhishig Burneebaatar, Naranbat Nymadawa, Satoshi Mitarai, Sarantuya Jav, Chen‐Yuan Chiang

2020Antimicrobial Agents and Chemotherapy17 citationsDOIOpen Access PDF

Abstract

Globally, mutations in the katG gene account for the majority of isoniazid-resistant strains of Mycobacterium tuberculosis . Buyankhishig et al. analyzed a limited number of Mycobacterium tuberculosis strains in Mongolia and found that isoniazid resistance was mainly attributable to inhA mutations (B. Buyankhishig, T. Oyuntuya, B. Tserelmaa, J. Sarantuya, et al., Int J Mycobacteriol 1:40–44, 2012, https://doi.org/10.1016/j.ijmyco.2012.01.007 ).

Topics & Concepts

IsoniazidINHAMycobacterium tuberculosisTuberculosisMicrobiologyVirologyBiologyGeneticsMedicinePathologyTuberculosis Research and EpidemiologyMycobacterium research and diagnosisDiagnosis and treatment of tuberculosis
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