Targeting BRD4 to attenuate RANKL-induced osteoclast activation and bone erosion in rheumatoid arthritis

Changyao Wang, Han Zhang, Xiangyu Wang, Xiao Ma, Jian Zhang, Yongtao Zhang

2024Molecular and Cellular Biochemistry12 citationsDOI

Topics & Concepts

MedicineOsteoclastRheumatoid arthritisBone resorptionRANKLInflammationArthritisCancer researchRheumatologyOsteolysisImmunologyPathologyInternal medicineSurgeryReceptorActivator (genetics)Protein Degradation and InhibitorsMultiple Myeloma Research and TreatmentsPeptidase Inhibition and Analysis