Dexmedetomidine Regulates Autophagy via the AMPK/mTOR Pathway to Improve SH-SY5Y-APP Cell Damage Induced by High Glucose
Pinzhong Chen, Xiaohui Chen, Honghong Zhang, Jianghu Chen, Mingxue Lin, Haitao Qian, Fei Gao, Yisheng Chen, Cansheng Gong, Xiaochun Zheng, Ting Zheng
Topics & Concepts
AutophagyAMPKSH-SY5YPI3K/AKT/mTOR pathwayViability assayNeuroprotectionNeurotoxicityChemistryCell biologyApoptosisProtein kinase BWortmanninSignal transductionBiologyPhosphorylationPharmacologyCell cultureProtein kinase ABiochemistryNeuroblastomaToxicityGeneticsOrganic chemistryAutophagy in Disease and TherapyAlzheimer's disease research and treatmentsTryptophan and brain disorders