Expanded porphyrins: functional photoacoustic imaging agents that operate in the NIR-II region
Jingqin Chen, Adam C. Sedgwick, Sajal Sen, Yaguang Ren, Qinchao Sun, Calvin V. Chau, Jonathan F. Arambula, Tridib Sarma, Liang Song, Jonathan L. Sessler, Chengbo Liu
Abstract
In this study, two expanded porphyrins, octaphyrin and naphthorosarin were evaluated as potential PA agents. The nanoparticle encapsulation of octaphyrin successfully enabled the visualization of acidic environments and the discrimination between cancerous and healthy tissues.
Topics & Concepts
Photoacoustic imaging in biomedicineImaging agentChemistryNanotechnologyCombinatorial chemistryMaterials scienceOpticsPhysicsBiologyIn vivoBiotechnologyPhotoacoustic and Ultrasonic ImagingNanoplatforms for cancer theranosticsThermography and Photoacoustic Techniques