Autosomal Dominant Polycystic Kidney Disease Prevalence among a Racially Diverse United States Population, 2002 through 2018
Thet T. Aung, Simran K. Bhandari, Qiaoling Chen, Fatima T Malik, Cynthia J. Willey, Kristi Reynolds, Steven J. Jacobsen, John J. Sim
Abstract
Among a large racially and ethnically diverse US population, the prevalence of diagnosed ADPKD between 2002 and 2018 was 42.6 per 100,000 persons.ADPKD prevalence (per 100,000) was higher in (non-Hispanic) White (63.2) and Black (73.0) patients compared with Hispanic (39.9) and Asian (48.9) patients.Given the variable penetrance of ADPKD, our findings suggest race may be a factor in the clinical presentation and diagnosis of ADPKD.
Topics & Concepts
MedicinePenetranceAutosomal dominant polycystic kidney diseaseRace (biology)Ethnically diverseDiseaseEpidemiologyDemographyRisk factorWhite (mutation)Ethnic groupNegroidIncidence (geometry)Public healthKidney diseasePopulationPrevalenceNon-Hispanic whitesPresentation (obstetrics)Cross-sectional studyConcordanceInternal medicinePediatricsGenetic and Kidney Cyst DiseasesRenal Diseases and GlomerulopathiesPediatric Urology and Nephrology Studies