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Recent progress in the radical α-C(sp<sup>3</sup>)–H functionalization of ketones

Jiao‐Zhe Li, Weikang Zhang, Guo‐Ping Ge, Hongxing Zheng, Wen‐Ting Wei

2021Organic & Biomolecular Chemistry26 citationsDOI

Abstract

)-H functionalization of ketones, with an emphasis on radical initiation systems and possible mechanisms of the transformations. The application of these strategies is illustrated by the synthesis of several biologically active molecules and drug molecules. Further subdivision is based on substrate type and reaction type.

Topics & Concepts

ChemistrySurface modificationKetoneRadicalCombinatorial chemistryMoleculeSubstrate (aquarium)Organic chemistryOceanographyPhysical chemistryGeologyCatalytic C–H Functionalization MethodsRadical Photochemical ReactionsSulfur-Based Synthesis Techniques
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