<i>In Vivo</i> Effectiveness of Several Antimicrobial Locks To Eradicate Intravascular Catheter Coagulase-Negative Staphylococci Biofilms
Andrés Blanco-Di Matteo, Nuria Garcı́a-Fernández, Aitziber Aguinaga Pérez, Francisco Carmona-Torre, Amaya C. Oteiza, José Leiva, José Luís del Pozo
Abstract
Tunneled central venous catheter (TCVC) related infection remains a challenge in the care of hemodialysis patients. We aimed to determine the best antimicrobial lock therapy (ALT) to eradicate coagulase-negative staphylococci (CoNS) biofilms.
Topics & Concepts
CoagulaseAntimicrobialMicrobiologyBiofilmCentral venous catheterCatheterMedicineHemodialysis CatheterStaphylococcus aureusIn vivoStaphylococcal infectionsBiologyIntensive care medicineStaphylococcusSurgeryBacteriaBiotechnologyGeneticsCentral Venous Catheters and HemodialysisStreptococcal Infections and TreatmentsAntibiotics Pharmacokinetics and Efficacy