Litcius/Paper detail

Continuous flow synthesis and post-synthetic conversion of single-crystalline covalent organic frameworks

Michael Traxler, William R. Dichtel

2024Chemical Science31 citationsDOIOpen Access PDF

Abstract

. Additionally, the versatility of the continuous flow reaction approach was demonstrated on a post-synthetic single crystal to single crystal demethylation of CF-TAPB-DMPDA to afford a hydroxyl functionalized COF CF-TAPB-DHPDA. Throughout the modification process, the material maintained its hexagonal morphology, crystallinity, and porosity. This work reports the first example of synthesizing and post-synthetically modifying imine linked COF single crystals in continuous flow and will prove a first step towards scaling high quality COFs to industrial levels.

Topics & Concepts

Continuous flowOrganic synthesisCovalent bondFlow (mathematics)Combinatorial chemistryChemistryMaterials scienceNanotechnologyOrganic chemistryBiochemical engineeringEngineeringMathematicsCatalysisGeometryCovalent Organic Framework ApplicationsMetal-Organic Frameworks: Synthesis and ApplicationsAdvanced Photocatalysis Techniques