Natural protoberberine alkaloids, identified as potent selective LSD1 inhibitors, induce AML cell differentiation
Zhongrui Li, Feng‐Zhi Suo, Yan-Jia Guo, Hai-Fang Cheng, Sheng-Hui Niu, Dandan Shen, Lijuan Zhao, Zhenzhen Liu, Mamun Maa, Bin Yu, Yi‐Chao Zheng, Hong‐Min Liu
Topics & Concepts
IsoquinolineChemistryMyeloid leukemiaCell growthPharmacologyCD86In vivoBiochemistryStereochemistryCancer researchBiologyPhenotypeGeneBiotechnologyEpigenetics and DNA MethylationCancer therapeutics and mechanismsHistone Deacetylase Inhibitors Research