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MeganServer: facilitating interactive access to metagenomic data on a server

Anupam Gautam, Wenhuan Zeng, Daniel H. Huson

2023Bioinformatics25 citationsDOIOpen Access PDF

Abstract

MOTIVATION: Metagenomic projects often involve large numbers of large sequencing datasets (totaling hundreds of gigabytes of data). Thus, computational preprocessing and analysis are usually performed on a server. The results of such analyses are then usually explored interactively. One approach is to use MEGAN, an interactive program that allows analysis and comparison of metagenomic datasets. Previous releases have required that the user first download the computed data from the server, an increasingly time-consuming process. Here, we present MeganServer, a stand-alone program that serves MEGAN files to the web, using a RESTful API, facilitating interactive analysis in MEGAN, without requiring prior download of the data. We describe a number of different application scenarios. AVAILABILITY AND IMPLEMENTATION: MeganServer is provided as a stand-alone program tools/megan-server in the MEGAN software suite, available at https://software-ab.cs.uni-tuebingen.de/download/megan6. Source is available at: https://github.com/husonlab/megan-ce/tree/master/src/megan/ms. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.

Topics & Concepts

Computer scienceDownloadPreprocessorSoftwareSoftware suiteMetagenomicsSuiteWeb serverTree (set theory)Process (computing)Data pre-processingOperating systemData miningDatabaseWorld Wide WebThe InternetProgramming languageGeneChemistryArchaeologyHistoryMathematicsBiochemistryMathematical analysisGenomics and Phylogenetic StudiesGene expression and cancer classificationScientific Computing and Data Management
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