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Sphingosylphosphorylcholine ameliorates doxorubicin-induced cardiotoxicity in zebrafish and H9c2 cells by reducing excessive mitophagy and mitochondrial dysfunction

Jinrun Zhou, Yao Lu, Zhiliang Li, Zhaohui Wang, Weihua Kong, Jing Zhao

2022Toxicology and Applied Pharmacology18 citationsDOI

Topics & Concepts

MitophagyCardiotoxicityPINK1DoxorubicinParkinPharmacologyApoptosisZebrafishMitochondrionAutophagyProgrammed cell deathChemistryCell biologyCancer researchBiologyChemotherapyMedicineBiochemistryInternal medicineParkinson's diseaseDiseaseGeneMitochondrial Function and PathologyATP Synthase and ATPases ResearchElectron Spin Resonance Studies
Sphingosylphosphorylcholine ameliorates doxorubicin-induced cardiotoxicity in zebrafish and H9c2 cells by reducing excessive mitophagy and mitochondrial dysfunction | Litcius