Phototriggered Self-Catalyzed Phosphorylation of 3,4-Dihydroquinoxalin-2(1<i>H</i>)-ones with Diarylphosphine Oxides in EtOH
Yanfang Jiang, Wen‐Tao Ouyang, Hong‐Tao Ji, Jia-Cheng Hou, Ting Li, Qing-Xia Luo, Chao Wu, Li‐Juan Ou, Wei‐Min He
Abstract
A highly effective external photocatalyst- and additive-free method for the phosphorylation of 3,4-dihydroquinoxalin-2(1 H )-ones to produce phosphorylated dihydroquinoxalin-2(1 H )-ones has been reported. A wide variety of phosphorylated products were formed in good to excellent yields. Preliminary mechanistic studies reveal that the phosphorylation process involves an EnT process, a SET process, a HAT process, and a deprotonation process.
Topics & Concepts
CatalysisChemistryPhosphorylationCombinatorial chemistryOrganic chemistryBiochemistryFluorine in Organic ChemistrySynthesis and Catalytic ReactionsCatalytic C–H Functionalization Methods