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Radical spirocyclization of biaryl ynones for the construction of NO<sub>2</sub>-containing spiro[5.5]trienones

Dong Xia, Liu‐Yu Shen, Yicheng Zhang, Wenchao Yang

2022New Journal of Chemistry13 citationsDOI

Abstract

An efficient 6- exo-trig radical cascade reaction of biaryl ynones with NaNO 2 was developed to afford nitro-functionalized spiro[5.5]trienones with yields of up to 88%.

Topics & Concepts

ChemistryCombinatorial chemistryStereochemistryRadical Photochemical ReactionsCatalytic C–H Functionalization MethodsOxidative Organic Chemistry Reactions
Radical spirocyclization of biaryl ynones for the construction of NO<sub>2</sub>-containing spiro[5.5]trienones | Litcius