Ferroptosis hijacking by Mycobacterium tuberculosis
Boyi Gan
Abstract
A recent study from Nature Communications reveals that Mycobacterium tuberculosis can hijack epigenetic machinery in host cells and induce host cell ferroptosis, which promotes pathogen pathogenicity and spread. These findings also suggest new therapeutic strategies to treat tuberculosis.
Topics & Concepts
TuberculosisMycobacterium tuberculosisPathogenicityPathogenEpigeneticsHost (biology)BiologyMicrobiologyVirologyGeneticsMedicineGenePathologyFerroptosis and cancer prognosisRNA modifications and cancerEpigenetics and DNA Methylation