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Cholesterol access in cellular membranes controls Hedgehog signaling

Arun Radhakrishnan, Rajat Rohatgi, Christian Siebold

2020Nature Chemical Biology154 citationsDOIOpen Access PDF

Topics & Concepts

SmoothenedPTCH1HedgehogPatchedCell biologyBiologyG protein-coupled receptorSignal transductionHedgehog signaling pathwayMembrane proteinCell signalingBiochemistryMembraneHedgehog Signaling Pathway StudiesEpigenetics and DNA MethylationGenomics and Chromatin Dynamics
Cholesterol access in cellular membranes controls Hedgehog signaling | Litcius