<i>In vitro</i> and <i>in vivo</i> antitumor activity of novel half-sandwich ruthenium complexes containing quinoline derivative ligands
Xiangdong He, Jun Chen, Martha Kandawa-Shultz, Guoqiang Shao, Yihong Wang
Abstract
results showed that the complex had excellent biological effects in tested mouse samples as the body weight of mice did not change much during the treatment, and the mean tumor volume was significantly lower than the control group.
Topics & Concepts
QuinolineIn vivoChemistryRutheniumRuthenium redIn vitroReactive oxygen speciesApoptosisCell cultureBiophysicsStereochemistryBiochemistryBiologyOrganic chemistryGeneticsBiotechnologyCalciumCatalysisMetal complexes synthesis and propertiesAdvanced biosensing and bioanalysis techniquesClick Chemistry and Applications