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Mitochondrial single-cell ATAC-seq for high-throughput multi-omic detection of mitochondrial genotypes and chromatin accessibility

Caleb A. Lareau, Vincent Liu, Christoph Muus, Samantha D. Praktiknjo, Lena Nitsch, Pauline Kautz, Katalin Sándor, Yajie Yin, Jacob C. Gutierrez, Karin Pelka, Ansuman T. Satpathy, Aviv Regev, Vijay G. Sankaran, Leif S. Ludwig

2023Nature Protocols72 citationsDOIOpen Access PDF

Topics & Concepts

BiologyComputational biologyChromatinHeteroplasmyMitochondrial DNASingle-cell analysisGeneticsSingle cell sequencingCellGenePhenotypeExome sequencingSingle-cell and spatial transcriptomicsCancer Genomics and DiagnosticsCRISPR and Genetic Engineering
Mitochondrial single-cell ATAC-seq for high-throughput multi-omic detection of mitochondrial genotypes and chromatin accessibility | Litcius