Mitochondrial single-cell ATAC-seq for high-throughput multi-omic detection of mitochondrial genotypes and chromatin accessibility
Caleb A. Lareau, Vincent Liu, Christoph Muus, Samantha D. Praktiknjo, Lena Nitsch, Pauline Kautz, Katalin Sándor, Yajie Yin, Jacob C. Gutierrez, Karin Pelka, Ansuman T. Satpathy, Aviv Regev, Vijay G. Sankaran, Leif S. Ludwig
Topics & Concepts
BiologyComputational biologyChromatinHeteroplasmyMitochondrial DNASingle-cell analysisGeneticsSingle cell sequencingCellGenePhenotypeExome sequencingSingle-cell and spatial transcriptomicsCancer Genomics and DiagnosticsCRISPR and Genetic Engineering