Electrochemical aminotrideuteromethylthiolation of isocyanides with anilines and CD<sub>3</sub>SSO<sub>3</sub>Na
Lin Zhao, Xinyu Zhou, Kemeng Zhang, Siyu Han, Ge Wu
Abstract
Herein, we describe an electrochemical strategy that enables the aminotrideuteromethylthiolation of isocyanides with anilines and CD 3 SSO 3 Na, providing an unprecedented route to access S -CD 3 isothioureas in satisfactory yields.
Topics & Concepts
ChemistryElectrochemistryIsocyanideCombinatorial chemistryNuclear chemistryMedicinal chemistryPhysical chemistryElectrodeSulfur-Based Synthesis TechniquesRadical Photochemical ReactionsFluorine in Organic Chemistry