Emergence of novel strains of Shigella flexneri associated with sexual transmission in adult men in England, 2019–2020
Timothy J. Dallman, Hannah Charles, Mateo Prochazka, Katy Sinka, Gwenda Hughes, Gauri Godbole, Claire Jenkins
Abstract
National surveillance of shigellosis in England revealed an increase in sexually transmitted Shigella flexneri in adult males in 2019 that persisted throughout 2020. We observed a resurgence of azithromycin-resistant S. flexneri serotype 3a, and the emergence of two novel multidrug-resistant clades of S. flexneri 2a and S. flexneri 1b.
Topics & Concepts
Shigella flexneriShigellosisSerotypeAzithromycinMicrobiologyBiologyTransmission (telecommunications)VirologyCladeShigellaAntibioticsBacteriaSalmonellaGeneticsGeneEscherichia coliElectrical engineeringEngineeringPhylogenetic treeEscherichia coli research studiesViral gastroenteritis research and epidemiologyClostridium difficile and Clostridium perfringens research