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A Novel Approach of Targeting Linezolid Nanoemulsion for the Management of Lymph Node Tuberculosis

Anam Choudhary, Pooja Jain, Sradhanjali Mohapatra, Gulam Mustafa, Mohammad Javed Ansari, Mohammed F. Aldawsari, Ahmed Alalaiwe, Mohd. Aamir Mirza, Zeenat Iqbal

2022ACS Omega20 citationsDOIOpen Access PDF

Abstract

studies conducted on Wistar rats confirms the lymphatic targeting with a high amount of drug at the target organ just after 8 h of dosing. As a result of the foregoing promising results, it may be inferred that the suggested nanoemulsion could be a viable therapy option for lymph node tuberculosis.

Topics & Concepts

TuberculosisMedicinePharmacologyLymphMycobacterium tuberculosisIsoniazidLocal lymph node assayLymph nodeAntibioticsPyrazinamideImmunologyMicrobiologyPathologyBiologySkin sensitizationSensitizationDrug Solubulity and Delivery SystemsAdvanced Drug Delivery SystemsInhalation and Respiratory Drug Delivery
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