Co-encapsulation of collagenase type I and silibinin in chondroitin sulfate coated multilayered nanoparticles for targeted treatment of liver fibrosis
Jingwen Luo, Zhiwei Zhang, Yingchun Zeng, Yanming Dong, Lixin Ma
Topics & Concepts
Hepatic stellate cellCollagenaseSilibininChondroitin sulfateExtracellular matrixChemistryFibrosisHepatic fibrosisChondroitinType I collagenCirrhosisCancer researchPathologyGlycosaminoglycanBiochemistryMedicineInternal medicineEnzymeLiver physiology and pathologyProteoglycans and glycosaminoglycans researchLiver Disease Diagnosis and Treatment