Computational design of an efficient and thermostable esterase for polylactic acid depolymerization
Bin Xie, Jun Zhang, Huashan Sun, Rongrong Bai, Diannan Lu, Yushan Zhu, Weiliang Dong, Jie Zhou, Min Jiang
Abstract
A high-performance variant of PLA depolymerase, RPA1511, designated R5, was engineered using combinatorial computational design tools to facilitate closed-loop recycling of PLA waste.
Topics & Concepts
DepolymerizationPolylactic acidEsteraseChemistryOrganic chemistryEnzymePolymerManufacturing Process and Optimizationbiodegradable polymer synthesis and properties