Interleukin-6 sensitizes TNF-α and TRAIL/Apo2L dependent cell death through upregulation of death receptors in human cancer cells
Emiko Sano, Akira Kazaana, Hisashi Tadakuma, Toshiaki Takei, Sodai Yoshimura, Yuya Hanashima, Yoshinari Ozawa, Atsuo Yoshino, Yutaka Suzuki, Takuya Ueda
Topics & Concepts
ApoptosisDownregulation and upregulationCancer researchTumor necrosis factor alphaProgrammed cell deathCaspaseCancer cellFlow cytometryInterleukinCaspase 8ReceptorMelanomaUVB-induced apoptosisCytokineImmunologyChemistryMedicineCancerInternal medicineGeneBiochemistryCell death mechanisms and regulationinterferon and immune responsesCytokine Signaling Pathways and Interactions