Application of Box–Behnken design combined response surface methodology to optimize HPLC and spectrophotometric techniques for quantifying febuxostat in pharmaceutical formulations and spiked wastewater samples
Sk Manirul Haque, Habibur Rahman, Nafisur Rahman, Syed Najmul Hejaz Azmi, Omar Ashwaq, Saikh Mohammad Wabaidur, Masoom Raza Siddiqui, Mahboob Alam
Topics & Concepts
FebuxostatBox–Behnken designChromatographyResponse surface methodologyPlackett–Burman designFactorial experimentHigh-performance liquid chromatographyDetection limitChemistryComputer scienceMachine learningUric acidHyperuricemiaBiochemistryGout, Hyperuricemia, Uric AcidFungal Plant Pathogen ControlQuinazolinone synthesis and applications